Nature Cell Biology publication
Researcher Dr. Yi Jin and colleagues at Karolinska Institutet, Sweden, recently published their new findings on formation and malformation of blood vessels in high-impact Nature Cell Biology.
Gradientech’s CellDirector® 2D system was used to efficiently study flow-mediated migration of endothelial cells in vitro.
Their results show that the endoglin protein acts like a sensor that controls flow-directed migration in a dose-dependent manner, and is required for correct vascular morphogenesis. Vascular malfunction is a diverse and large clinical problem in many diseases and their new findings open up for further exciting drug targeting research.